One Chew, Triple Protection: Simparica Trio is the first FDA-approved monthly chewable that protects your dog against heartworm disease, ticks, fleas, roundworms, and hookworms. Approved for puppies as young as eight weeks old and weighing at least 2.8 pounds.

Heartworm Protection: Studies to support FDA-approval showed one dose provided 100% protection against heartworm disease.

Prevent Lyme Infections: Simparica Trio is the first FDA-approved product of its kind and the only one approved to prevent Lyme infections as a direct result of killing deer ticks. It’s proven to kill five types of ticks including the Gulf Coast Tick, Deer Tick, American Dog Tick, Lone Star Tick, Brown Dog Tick.

Kills Fleas & Intestinal Parasites: Prevents flea infestation by killing fleas before they can even lay eggs. Starts killing within 4 hours and achieved 100% effectiveness in 8 hours in a study. Treats roundworms and hookworms to protect your dog from intestinal parasites.

Satisfaction Guaranteed & Easy-to-Administer: Simparica Trio comes with a 100% satisfaction guarantee on prevention and is administered once a month with or without food. In a study 9 out of 10 dogs voluntarily consumed this tasty liver-flavored chew. ›  See more product details